01 - Preheat air fryer to 400°F for 3-5 minutes.
02 - Whisk together eggs and milk in a shallow bowl until combined.
03 - Combine panko breadcrumbs, Parmesan, garlic powder, paprika, black pepper, and salt in another shallow bowl.
04 - Dip each tilapia fillet into egg mixture, allowing excess to drip off, then press firmly into breadcrumb mixture to coat thoroughly.
05 - Lightly spray air fryer basket with oil. Arrange breaded fillets in single layer, cooking in batches if needed.
06 - Air fry for 10-12 minutes, flipping halfway through, until crust is golden brown and fish flakes easily with fork.
07 - Serve immediately, sprinkled with fresh parsley and accompanied by lemon wedges.